Owsley Stanley (1935–2011), also known as Owsley or Bear, "underground" LSD chemist and early Grateful Dead soundman, grandson of Augustus Owsley Stanley
Owsley (musician), the stage name of Will Owsley, American singer-songwriter and guitarist
Owsley (album), eponymous 1999 album by the singer-songwriter
Owsley, Missouri, an unincorporated community in Missouri, United States
Owsley County, Kentucky, a county in Kentucky, United States
